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American Society of Microbiology ABMM Exam Syllabus Topics:

American Society of Microbiology ABMM Sample Questions:

Question 1

A patient develops a severe diarrheal illness after consuming raw seafood. Stool culture yields a Gram- negative, comma-shaped bacterium that is oxidase-positive and grows on thiosulfate-citrate-bile salts-sucrose (TCBS) agar, producing blue-green colonies. The MOST significant virulence factor contributing to the severe, cholera-like diarrhea caused by this organism is:

A. Cholera toxin (CT)-like enterotoxin
B. Type III secretion system (T3SS)
C. Heat-labile toxin (LT)
D. Heat-stable enterotoxin (ST)

Question 2

An acid-fast bacillus isolate recovered from a respiratory specimen after 3 weeks of incubation on Löwenstein- Jensen medium is initially non-pigmented when grown in the dark. After exposure to light for several hours, the colonies develop a distinct yellow-orange pigment. This organism is classified as a:

A. Scotochromogen
B. Photochromogen
C. Nonchromogen
D. Rapid grower

Question 3

A clinical microbiology laboratory is performing quality control on antimicrobial susceptibility testing. The zone diameter for Escherichia coli ATCC 25922 tested against ciprofloxacin is consistently smaller than the acceptable range published by CLSI. The MOST likely cause of this discrepancy is:

A. All of the above
B. Incubation at an incorrect temperature
C. Inoculation with a bacterial suspension that is too dense
D. Use of expired antibiotic disks

Question 4

A clinical microbiology laboratory is evaluating a new rapid diagnostic test for influenza viruses. The test has a high sensitivity but a lower specificity compared to RT-PCR. In a setting with a low prevalence of influenza, the use of this rapid test is MOST likely to result in a high number of:

A. True positive results
B. False positive results
C. False negative results
D. True negative results

Question 5

A research laboratory is investigating the mechanism of action of a novel antiviral drug against herpes simplex virus. The drug is found to inhibit the viral DNA polymerase. Which of the following commercially available antiviral agents has a similar mechanism of action?

A. Amantadine
B. Acyclovir
C. Oseltamivir
D. Interferon-alpha

Solutions: